Biologic Association Summit

Wednesday, July 7, 2021 • 8 a.m. – 5 p.m.

Fee: $350 EB I $450 S

AOSSM and AANA welcome the Biologic Association (BA) 2nd Annual Summit to Nashville this July. The BA Summit agenda features renowned faculty delivering state-of-the-art presentations focused on innovative approaches and new orthobiologic ideas, products and applications. Summit participants include all multilevel and multidisciplinary stakeholders comprising a diverse group of scientists, clinicians, regulators, corporate, private equity and venture capitalists.

You may register for only the Biologic Association Summit or add onto your AOSSM-AANA Combined 2021 Annual Meeting registration and attend both!

Learning Objectives:

Upon completion of this educational activity, participants should be able to:

Contrast the different types of platelet rich plasma (PRP), including leukocyte-rich and leukocyte-poor PRP, with respect to clinical indication and efficacy.
Compare biologic agents and their indication(s) for treatment of pathologies of tendon, cartilage, ligament, and bone, including subchondral bone lesions.
Describe potential complications associated with the use of biologics for musculoskeletal pathologies and ways in which to avoid them.

Agenda

Time	Title
8 - 8:10 a.m.	Welcome (Michael G. Ciccotti, MD, Brian J. Cole, MD, MBA)
8:10 - 8:25 a.m.	BA Annual Update (Jason L. Dragoo, MD. Bert R. Mandelbaum, MD)
8:25 - 10:30 a.m.	Current Perspectives on the Use of Biologics in Clinical Practice Jorge Chahla, MD, PhD, Rachel M. Frank, MD, Seth L. Sherman, MD
	PRP: LP-PRP vs A2M for the Treatment of OA Symptoms Elizaveta Kon, MD, Kenneth R. Mautner, MD BMA/BMC – The Future of Bone Marrow Cellular Therapy Don Buford Jr, MD, Shane A. Shapiro, MD Modern Treatment of Subchondral Bone Lesions Bert R. Mandelbaum, MD, Jorge Chahla, MD, PhD Adipose Tissue: How Much Processing is Required (is culture necessary)? Daniel B. Saris, MD, PhD, Gerard A. Malanga, MD Allograft Biologics: Amnion, Allograft Cells John M. Tokish, MD, Jack Farr II, MD New Generation Pharmacologic Biologic Therapy Bert R. Mandelbaum, MD, Susanna Chubinskaya, PhD Lessons from Non-Orthopaedic Specialists J. Peter Rubin, MD, Lisa A. Fortier, DVM, PhD Q&A
10:30 - 10:40 a.m.	Exhibitor Break
10:45 a.m. - 12:45 p.m.	The Next Generation of Biologics - Cutting Edge Research Kurt P. Spindler, MD, Constance R. Chu, MD
	KEYNOTE Presentation: Basic Science Discoveries Ready for Clinical Translation Arnold Caplan, PhD Q&A Session Introduction: OrthoBiologic Research in 2020 - The Best of the Best Kurt P. Spindler, MD Quantification and Qualification of Stem Cells from Blood after Mobilization with Filgrastim, and Concentration Using a PRP System Anz AW, Matuska A, Edison JL, Abdullah SF, Dekker TJ, Plummer HA, Brock KV, Goodlett MD Recent Progress on Developing Exogenous Monocyte/Macrophage-Based Therapies for Inflammatory and Degenerative Diseases Chan MWY, Viswanathan S Platelet Rich Plasma Devices Can Be Used to Isolate Stem Cells from Synovial Fluid at the Point of Care Branch EA, Matuska AM, Plummer HA, Harrison RM, Anz AW Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis: An Expert Opinion and Proposal for a Novel Classification and Coding System Kon E, Di Matteo B, Delgado D, Cole BJ, Dorotei A, Dragoo JL, Filardo G, Fortier LA, Giuffrida A, Jo CH, Magalon J, Malanga GA, Mishra A, Nakamura N, Rodeo SA, Sampson S, Sánchez M Q&A KEYNOTE Presentation: Inducible (iPS) Stem Cells. When Can We Use Them Clinically? Clive N. Svendsen, PhD KEYNOTE Presentation: Future Directions in Data Collection Following Regenerative Procedures Gerard A. Malanga, MD Q&A
12:45 - 1:30 p.m.	Lunch Break
1:30 - 3:10 p.m.	Real-Life Practice Issues Scott A. Rodeo, MD
	How to Avoid Complications When Using OrthoBiologics What are the Complications, and Where are they Coming From? Scott A. Rodeo, MD Adipose Complication Jason L. Dragoo, MD BMA/BMC Complication David C. Karli, MD PRP Complication David C.Flanigan, MD Allograft (amnion) Complication Alberto J. Panero, DO Subchondral Bone Treatment Complication Christopher J. Williams, MD Q&A Pro vs Con Is Surgery Necessary to Achieve Optimal Results Louis F. McIntyre, MD, Don Buford Jr, MD Panel Discussion: Cost Effectiveness and Business of Biologics Brian J. Cole, MD, MBA, Bert R. Mandelbaum, MD, Claude T. Moorman III, MD, Kevin D. Plancher, MD, MPH, Mark H. Getelman, MD Panel Discussion: Ethics of OrthoBiologics Christian Lattermann, MD, William N. Levine, MD, Nikhil N. Verma, MD, Kenneth R. Zaslav, MD Q&A
3:10 - 3:25 p.m.	Exhibitor Break
3:25 - 5:20 p.m.	Live Moderated (Pre-Recorded) Biologic Procedure Demos Kenneth R. Zaslav, MD; John M. Tokish, MD
	Autologous Orthobiologics Office- Based Procedures and FDA Considerations Joanne Halbrecht, MD Demos: Biologics for Chondral Defect BMAC Alberto Gobbi, MD Adipose Daniel B. Saris, MD, PhD Coral Seth L. Sherman, MD Demos: Biologics for Rotator Cuff Repair BioInductive Collagen Implant Felix H. Savoie III, MD Patch Augmentation John M. Tokish, MD BMC for RCR Brian J. Cole, MD, MBA Demo: Biologics for ACL Reconstruction/Augmentation Adam W. Anz, MD Demo: Biologics for Subchondral Bone Lesions Rachel M. Frank, MD Demos: Adipose Processing Techniques Subcutaneous lipoaspiration Claude T. Moorman III, MD Arthroscopic Jason L. Dragoo, MD Demo: Subacromial Bursal Cell Harvest and Processing Augustus Mazzocca, MD, MS Biologics in Athletes - What Are the Elite Athletes Getting? Throwing Athletes (Elbows): What Are YOU Using on Your Team? James P. Bradley, MD Achy Knees in the NBA, NFL, NHL, MLS, MLB: What is Your Go-To Injection? Robin V. West, MD Achy Shoulders in the NBA, NFL, NHL, MLS, MLB: What is Your Go-To Injection? William N. Levine, MD Q&A Closing Remarks and Adjourn

Visit the Biologic Association site for more information.